Usage of Mesenchymal Stem Cells
Advantages in use of Mesenchymal Stem Cells (MSCs)
MSCs are multipotent stem cells that can differentiate into a variety of cell types, including: osteoblasts (bone cells), chondrocytes (cartilage cells) and adipocytes (fat cells).
Here are some key facts about MSCs and why transplant of MSCs is gaining greater acceptance in the treatment of various health conditions and diseases.
- Mesenchymal stem cells are capable of self-renewal and differentiation into various connective tissue lineages.
- Mesenchymal stem cells (MSCs) have been isolated from bone marrow, periosteum, trabecular bone, adipose tissue, synovium, skeletal muscle and deciduous teeth
- These cells have the capacity to differentiate into cells of connective tissue lineages, including bone, fat, cartilage and muscle.
- MSCs can also express phenotypic characteristics of endothelial, neural, smooth muscle, skeletal myoblasts, and cardiac myocyte cells.
- When induced into the infarcted heart, MSCs prevent deleterious remodeling and improve recovery
- Clinical use of cultured human MSCs (hMSCs) has begun for cancer patients, and recipients have received autologous or allogeneic MSCs
- MSCs can be used allogeneically, delivered systemically, and differentiate into a cardiomyocyte-like phenotype when implanted in healthy myocardium
- MSCs can be readily transduced by a variety of vectors and maintain transgene expression after in vivo differentiation.
Want to understand more about the use of MSCs and the benefits of cord blood banking? Contact us now for a no-obligation consultation with one of our experienced consultants.